OxyContin® is the controlled-release
formula of oxycodone hydrochloride, Oxycodone is in a class of drugs
called narcotic analgesics. Narcotic analgesics act in the central
nervous system (CNS) to relieve pain. Some of their side effects are
also caused by actions in the CNS. If a narcotic is used for a long
time, it may become habit-forming (causing mental or physical
dependence). Physical dependence may lead to withdrawal side effects
when you stop taking the medicine. OxyContin®
is used to treat chronic moderate-to-severe pain. Because it is a
controlled-release formula the tablets should never be cut, chewed, or
Before Using This Medicine
In deciding to use a medicine, the risks
of taking the medicine must be weighed against the good it will do. This
is a decision you and your doctor will make. For narcotic analgesics,
the following should be considered:
Tell your doctor if you have ever had any unusual or allergic
reaction to any of the narcotic analgesics. Also tell your health care
professional if you are allergic to any other substances, such as foods,
preservatives, or dyes.
FDA pregnancy category B. This means that it is unlikely to cause
birth defects. However, oxycodone may cause addiction and withdrawal
symptoms, difficulty breathing, as well as other harmful effects in a
newborn baby when taken during pregnancy. Do not take oxycodone without
first talking to your doctor if you are pregnant.
Oxycodone may cause addiction and withdrawal symptoms, difficulty
breathing, and sedation in a nursing infant. Do not take oxycodone
without first talking to your doctor if you are breast-feeding a baby.
Breathing problems may be especially likely to occur in children
younger than 2 years of age. These children are usually more sensitive
than adults to the effects of narcotic analgesics. Also, unusual
excitement or restlessness may be more likely to occur in children
receiving these medicines.
Elderly people are especially sensitive to the effects of narcotic
analgesics. This may increase the chance of side effects, especially
breathing problems, during treatment.
Oxycodone may increase the
effects of other drugs that cause drowsiness. Dangerous sedation,
dizziness, or drowsiness may occur if oxycodone is taken with any of
these medications, including:
- pain relievers
- anxiety medicines
- seizure medicines
- muscle relaxants.
Other medical problems-
Oxycodone is habit forming and
should only be used under close supervision by patients with an alcohol
or drug addiction. Be sure to tell your doctor if you have:
- kidney disease
- liver disease
- urinary retention
- an enlarged prostate
- seizures or epilepsy
- gallbladder disease
- head injury
- Addison's disease
Proper Use of This Medicine
It is important to use this
- Take oxycodone exactly as directed
by your doctor. If you do not understand these directions, ask your
pharmacist, nurse, or doctor to explain them to you.
- Take each dose with a full glass of
- Oxycodone can be taken with food or
milk if stomach upset occurs.
- Never take more oxycodone than is
prescribed for you. Taking too much oxycodone could result in serious
side effects, even death. If your pain is not being adequately
treated, talk to your doctor.
- Do not crush, chew, or break
controlled-release forms of oxycodone such as Oxycontin. Swallow them
whole. They are specially formulated to release oxycodone slowly into
your system. Breaking them would cause too much drug to be released
into the blood at one time leading to a potentially fatal dose of
- Occasionally, empty Oxycontin
tablets may be passed out in the stool. This is not a problem. The
active medication has been absorbed in the body and the empty tablet
shell may appear in the stool.
- To ensure that you get a correct
dose, measure the liquid form of oxycodone with a special
dose-measuring spoon or cup, not with a regular table spoon. If you do
not have a dose-measuring device, ask your pharmacist where you can
- Do not stop taking oxycodone
suddenly if you have been taking it continuously for more than 5 to 7
days. Stopping suddenly could cause withdrawal symptoms and make you
uncomfortable. Your doctor may want to gradually reduce the dose.
- Increasing the amount of fiber and
water (six to eight full glasses) in your diet may alleviate
- Do not share this medication with
The dose of citalopram will be different for different
patients. Follow your doctor's orders or the directions on the label.
The following information includes only the average doses of citalopram.
If your dose is different, do not change it unless your doctor tells you
to do so.
The number of tablets that you take depends on the strength of the
Adults—Your doctor will determine the dose
according to your individual needs. To be helpful, these medicines need
to be taken two times a day at regularly scheduled times.
Children—Use and dose must be determined
by your doctor.
Take the missed dose as soon as you
remember. Do not take a double dose of this medication. Wait the
prescribed amount of time before taking the next dose.
To store this medicine:
- Keep out of the reach of children.
Overdose is very dangerous in young children.
Store away from heat and direct light.
Do not store tablets or capsules in the
bathroom, near the kitchen sink, or in other damp places. Heat or
moisture may cause the medicine to break down.
Do not keep outdated medicine or medicine
no longer needed. Be sure that any discarded medicine is out of the
reach of children.
Precautions While Using This Medicine
If you will be taking this medicine for a
long time (for example, for several months at a time), your doctor
should check your progress at regular visits.
Narcotic analgesics will add to the
effects of alcohol and other CNS depressants (medicines that slow down
the nervous system, possibly causing drowsiness). Some examples of CNS
depressants are antihistamines or medicine for hay fever, other
allergies, or colds; sedatives, tranquilizers, or sleeping medicine;
other prescription pain medicines including other narcotics;
barbiturates; medicine for seizures; muscle relaxants; or anesthetics,
including some dental anesthetics. Do not drink alcoholic beverages, and
check with your medical doctor or dentist before taking any of the
medicines listed above, while you are using this medicine.
This medicine may cause some people to
become drowsy, dizzy, or lightheaded, or to feel a false sense of
well-being. Make sure you know how you react to this medicine before you
drive, use machines, or do anything else that could be dangerous if you
are dizzy or are not alert and clearheaded.
Dizziness, light-headedness, or fainting
may occur, especially when you get up suddenly from a lying or sitting
position. Getting up slowly may help lessen this problem.
Nausea or vomiting may occur, especially
after the first couple of doses. This effect may go away if you lie down
for a while. However, if nausea or vomiting continues, check with your
medical doctor or dentist. Lying down for a while may also help relieve
some other side effects, such as dizziness or light-headedness, that may
Before having any kind of surgery
(including dental surgery) or emergency treatment, tell the medical
doctor or dentist in charge that you are taking this medicine.
Narcotic analgesics may cause dryness of
the mouth. For temporary relief, use sugarless candy or gum, melt bits
of ice in your mouth, or use a saliva substitute. However, if dry mouth
continues for more than 2 weeks, check with your dentist. Continuing
dryness of the mouth may increase the chance of dental disease,
including tooth decay, gum disease, and fungus infections.
If you have been taking this medicine
regularly for several weeks or more, do not suddenly stop using it
without first checking with your doctor. Your doctor may want you to
reduce gradually the amount you are taking before stopping completely,
in order to lessen the chance of withdrawal side effects.
If you think you or someone else may have
taken an overdose, get emergency help at once .
Side Effects of This Medicine
Along with its needed effects,
a medicine may cause some unwanted effects. Although not all of these
side effects may occur, if they do occur they may need medical
Get emergency help immediately if any of the following symptoms of
- Cold, clammy skin; confusion;
convulsions (seizures); dizziness (severe); drowsiness (severe); low
blood pressure; nervousness or restlessness (severe); pinpoint pupils
of eyes; slow heartbeat; slow or troubled breathing; weakness (severe)
Also, check with your doctor as soon as
possible if any of the following side effects occur:
- Less common or rare: fast, slow, or
pounding heartbeat; feelings of unreality; hallucinations (seeing,
hearing, or feeling things that are not there); hives, itching, or
skin rash; increased sweating; irregular breathing; mental depression
or other mood or mental changes; ringing or buzzing in the ears;
shortness of breath, wheezing, or troubled breathing; swelling of
face; trembling or uncontrolled muscle movements; unusual excitement
or restlessness (especially in children)
Other side effects may occur that
usually do not need medical attention. These side effects may go away
during treatment as your body adjusts to the medicine. However, check
with your doctor if any of the following side effects continue or are
- More common: Dizziness,
light-headedness, or feeling faint; drowsiness; nausea or vomiting
- Less common: Blurred or double
vision or other changes in vision; constipation (more common with
long-term use and with codeine); decrease in amount of urine;
difficult or painful urination; dry mouth; false sense of well-being;
frequent urge to urinate; general feeling of discomfort or illness;
headache; loss of appetite; nervousness or restlessness; nightmares or
unusual dreams; stomach cramps or pain; trouble in sleeping; unusual
tiredness or weakness
After you stop using this medicine,
your body may need time to adjust. The length of time this takes depends
on the amount of medicine you were using and how long you used it.
During this period of time check with your doctor if you notice any of
the following side effects:
- Body aches; diarrhea; fast
heartbeat; fever, runny nose, or sneezing; gooseflesh; increased
sweating; increased yawning; loss of appetite ; nausea or vomiting;
nervousness, restlessness, or irritability; shivering or trembling;
stomach cramps; trouble in sleeping; unusually large pupils of eyes;
U.S. and Canada: OxyContin®