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treatment & management

Drug Profiles:
Gabapentin Tablets and Capsules
AKA: Neurontin® Tablets and Neurontin® Capsules

CAUTION: Federal law prohibits dispensing without prescription.

   

About the Drug:

Neurontin® is another Epilepsy medication that is being used as an effective preventive or prophylactic Migraine regiment. As Migraine and Epilepsy are Related diseases, this is actually a sound approach.  

Description:

Neurontin® is an antiepileptic drug, prescribed as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy. Neurontin is also indicated as adjunctive therapy in the treatment of partial seizures in pediatric patients age 3-12 years.. It is typically added to the treatment regimen when other drugs fail to fully control a patient's attacks.

Caution:

Do not abruptly stop taking Neurontin. If the drug isn't withdrawn gradually, seizures may be caused, even in patients who do not normally experience seizures.

Neurontin may cause dizziness, somnolence and other symptoms and signs of CNS depression. Accordingly, they should be advised neither to drive a car nor to operate other complex machinery until they have gained sufficient experience on Neurontin to gauge whether or not it affects their mental and/or motor performance adversely.
 

How one should take this medication:

It is important to take this medication exactly as prescribed. It can be taken with or without food. Avoid breaking the tablets; the medication has a bitter taste.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take two doses

at once.

--Storage instructions...

Store Neurontin® at room temperature in a tightly-closed container. Protect the tablets from moisture.

When Indicated for Migraine:

Since this is a relatively new way to use some of the newer neuronal stabilizers (anticonvulsants) such as Neurontin® (gabapentin) (As well as others such as Topamax® (topiramate), Lamictal® (lamotrigine) and Gabatril® (tiagabine)) prophylactically for Migraine disease, the dosage will be directed by your physican. Having noted that we will post recommend clinical practice guidelines for use as soon as we get that information from the manufacturer, FDA or AHS.

Possible Side Effects:

Some side effects, such as fatigue, are more likely to surface with high doses of Neurontin®. Others occur regardless of dosage. While many tend to disappear after the first 8 weeks of therapy, it's still important to report them to your doctor. Only your doctor can determine if it is safe for you to continue taking Neurontin®.

More common side effects may include:

Clumsiness or unsteadiness; continuous, uncontrolled, back-and-forth and/or rolling eye movements. In 3- to 12-year-old patients: aggressive behaviors or other behavior problems; anxiety; concentration problems and change in school performance; crying; false sense of well-being; hyperactivity or increase in body movements; mental depression; reacting too quickly, too emotionally, or overreacting; rapidly changing moods; restlessness; suspiciousness or distrust

Less common side effects may include:

depression, irritability, or other mood or mental changes; loss of memory 

When should this drug not be prescribed:

If Neurontin® gives you an allergic reaction, you'll be unable to use the drug.

Special warnings about this medication

Be sure to tell your doctor if you have any other medical conditions, especially kidney, liver, or heart disease

Possible food and drug interactions when taking this medication:

Antacids can lower the blood level of Neurontin, so Neurontin should be taken at least two hours after antacids. Gabapentin may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants.

Special Information if You Are Pregnant or Breastfeeding:

In animal studies, Neurontin® has caused harm to the developing fetus, and its safety has not been verified in pregnant humans. It is recommended for use during pregnancy only if the doctor feels that its potential benefit outweighs the potential risk to the infant.

This medication may appear in breast milk, and its possible effect on the nursing infant remains unknown. Check with your doctor if you plan to breastfeed your baby.

CHILDREN

The safety and effectiveness of Neurontin® for Migraine prevention in children have not been established.

Overdose:

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.


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