|
Some of these medicines are also used to
relieve other kinds of pain or to treat other painful conditions, such
as gout attacks; bursitis; tendinitis; sprains, strains, or other
injuries; or menstrual cramps. Ibuprofen and naproxen are also used to
reduce fever. Meclofenamate is also
used to reduce the amount of bleeding in some women who have very heavy
menstrual periods.
Nonsteroidal anti-inflammatory drugs may also be used to treat other
conditions as determined by your doctor.
Any nonsteroidal anti-inflammatory drug can cause side effects,
especially when it is used for a long time or in large doses. Some of
the side effects are painful or uncomfortable. Others can be more
serious, resulting in the need for medical care and sometimes even
death. If you will be taking this medicine for more than one or two
months or in large amounts, you should discuss with your doctor the good
that it can do as well as the risks of taking it. Also, it is a good
idea to ask your doctor about other forms of treatment that might help
to reduce the amount of this medicine that you take and/or the length of
treatment.
One of the nonsteroidal anti-inflammatory drugs, phenylbutazone, is
especially likely to cause very serious side effects. These serious side
effects are more likely to occur in patients 40 years of age or older
than in younger adults, and the risk becomes greater as the patient's
age increases. Before you take phenylbutazone, be sure that you have
discussed its use with your doctor. Also, do not use phenylbutazone to
treat any painful condition other than the one for which it was
prescribed by your doctor .
Although ibuprofen and naproxen may be used instead of aspirin to treat
many of the same medical problems, they must not be used by people who
are allergic to aspirin.
Oral
- Diclofenac
- Tablets (U.S. and Canada)
- Delayed-release tablets (U.S. and
Canada)
- Extended-release tablets (Canada)
- Diflunisal
- Tablets (U.S. and Canada)
- Etodolac
- Capsules (U.S.)
- Tablets (U.S.)
- Extended-release tablets (U.S.)
- Fenoprofen
- Capsules (U.S. and Canada)
- Tablets (U.S. and Canada)
- Floctafenine
- Flurbiprofen
- Extended-release capsules (Canada)
- Tablets (U.S. and Canada)
- Ibuprofen
- Oral suspension (U.S.)
- Tablets (U.S. and Canada)
- Chewable tablets (U.S.)
- Indomethacin
- Capsules (U.S. and Canada)
- Extended-release capsules (U.S.
and Canada)
- Oral suspension (U.S.)
- Ketoprofen
- Capsules (U.S. and Canada)
- Extended-release capsules (U.S.
and Canada)
- Tablets (U.S.)
- Delayed-release tablets (Canada)
- Extended-release tablets (Canada)
- Meclofenamate
- Mefenamic Acid
- Capsules (U.S. and Canada)
- Meloxicam
- Nabumetone
- Tablets (U.S. and Canada)
- Naproxen
- Oral suspension (U.S. and Canada)
- Tablets (U.S. and Canada)
- Delayed-release tablets (U.S. and
Canada)
- Extended-release tablets (U.S. and
Canada)
- Oxaprozin
- Tablets (U.S. and Canada)
- Phenylbutazone
- Capsules (U.S.)
- Tablets (U.S. and Canada)
- Buffered tablets (Canada)
- Piroxicam
- Capsules (U.S. and Canada)
- Sulindac
- Tablets (U.S. and Canada)
- Tenoxicam
- Tiaprofenic Acid
- Extended-release capsules (Canada)
- Tablets (Canada)
- Tolmetin
- Capsules (U.S. and Canada)
- Tablets (U.S. and Canada)
Rectal
- Diclofenac
- Indomethacin
- Suppositories (U.S. and Canada)
- Ketoprofen
- Naproxen
- Piroxicam
Before Using This Medicine
In deciding to use a medicine, the
risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your health care professional will make.
For the nonsteroidal anti-inflammatory drugs, the following should be
considered:
Allergies-
Tell your health care professional if you have ever had any unusual
or allergic reaction to any of the nonsteroidal anti-inflammatory drugs,
or to any of the following medicines:
- Aspirin or other salicylates
- Ketorolac (e.g., Toradol)
- Oxyphenbutazone (e.g., Oxalid,
Tandearil)
- Suprofen (e.g., Suprol)
- Zomepirac (e.g., Zomax)
Also tell your health care professional
if you are allergic to any other substances, such as foods,
preservatives, or dyes.
Diet—
Make certain your health care professional knows if you are on any
special diet, such as a low-sodium or low-sugar diet. Some of these
medicines contain sodium or sugar.
Pregnancy-
Studies on birth defects with
these medicines have not been done in humans. However, there is a chance
that these medicines may cause unwanted effects on the heart or blood
flow of the fetus or newborn baby if they are taken regularly during the
last few months of pregnancy. Also, studies in animals have shown that
these medicines, if taken late in pregnancy, may increase the length of
pregnancy, prolong labor, or cause other problems during delivery. If
you are pregnant, do not take any of these medicines, including
nonprescription (over-the-counter [OTC]) ibuprofen or naproxen, without
first discussing its use with your doctor.
Studies in animals have not shown that fenoprofen, floctafenine,
flurbiprofen, ibuprofen, ketoprofen, nabumetone, naproxen,
phenylbutazone, piroxicam, tiaprofenic acid, or tolmetin causes birth
defects. Diflunisal caused birth defects of the spine and ribs in
rabbits, but not in mice or rats. Diclofenac and meclofenamate caused
unwanted effects on the formation of bones in animals. Etodolac and
oxaprozin caused birth defects in animals. Indomethacin caused slower
development of bones and damage to nerves in animals. In some animal
studies, sulindac caused unwanted effects on the development of bones
and organs. Studies on birth defects with mefenamic acid have not been
done in animals.
Even though most of these medicines did not cause birth defects in
animals, many of them did cause other harmful or toxic effects on the
fetus, usually when they were given in such large amounts that the
pregnant animals became sick.
Breast-feeding-
- For indomethacin:
Indomethacin passes into the breast milk and has been reported to
cause unwanted effects in nursing babies.
- For meclofenamate: Use of
meclofenamate by nursing mothers is not recommended, because in animal
studies it caused unwanted effects on the newborn's development.
- For phenylbutazone:
Phenylbutazone passes into the breast milk and may cause unwanted
effects, such as blood problems, in nursing babies.
- For piroxicam: Studies in
animals have shown that piroxicam may decrease the amount of milk.
Although other anti-inflammatory
analgesics have not been reported to cause problems in nursing babies,
diclofenac, diflunisal, fenoprofen, flurbiprofen, meclofenamate,
mefenamic acid, naproxen, piroxicam, and tolmetin pass into the breast
milk. It is not known whether etodolac, floctafenine, ibuprofen,
ketoprofen, nabumetone, oxaprozin, sulindac, or tiaprofenic acid passes
into human breast milk.
Children-
- For ibuprofen: Ibuprofen has
been tested in children 6 months of age and older. It has not been
shown to cause different side effects or problems than it does in
adults.
- For indomethacin and for tolmetin:
Indomethacin and tolmetin have been tested in children 2 years of age
and older and have not been shown to cause different side effects or
problems than they do in adults.
- For naproxen: Studies with
naproxen in children 2 years of age and older have shown that skin
rash may be more likely to occur.
- For oxaprozin: Oxaprozin has
been used in children with arthritis. However, there is no specific
information comparing use of this medicine in children with use in
other age groups.
- For phenylbutazone: Use of
phenylbutazone in children up to 15 years of age is not recommended.
- For other anti-inflammatory
analgesics: There is no specific information on the use of other
anti-inflammatory analgesics in children.
Most of these medicines, especially
indomethacin and phenylbutazone, can cause serious side effects in any
patient. Therefore, it is especially important that you discuss with the
child's doctor the good that this medicine may do as well as the risks
of using it.
Older adults-
Certain side effects, such as confusion, swelling of the face, feet,
or lower legs, or sudden decrease in the amount of urine, may be
especially likely to occur in elderly patients, who are usually more
sensitive than younger adults to the effects of nonsteroidal
anti-inflammatory drugs. Also, elderly people are more likely than
younger adults to get very sick if these medicines cause stomach
problems. With phenylbutazone, blood problems may also be more likely to
occur in the elderly.
Other medicines-
Although certain medicines
should not be used together at all, in other cases two different
medicines may be used together even if an interaction might occur. In
these cases, your doctor may want to change the dose, or other
precautions may be necessary. When you are taking a nonsteroidal
anti-inflammatory drug, it is especially important that your health care
professional know if you are taking any of the following:
- Anticoagulants (blood thinners) or
- Cefamandole (e.g., Mandol) or
- Cefoperazone (e.g., Cefobid) or
- Cefotetan (e.g., Cefotan) or
- Heparin or
- Plicamycin (e.g., Mithracin) or
- Valproic acid—The chance of bleeding
may be increased
- Aspirin—The chance of serious side
effects may be increased if aspirin is used together with a
nonsteroidal anti-inflammatory drug on a regular basis
- Ciprofloxacin (e.g., Cipro) or
- Enoxacin (e.g., Penetrex) or
- Itraconazole (e.g., Sporanox) or
- Ketoconazole (e.g., Nizoral) or
- Lomefloxacin (e.g., Maxaquin) or
- Norfloxacin (e.g., Noroxin) or
- Ofloxacin (e.g., Floxin) or
- Tetracyclines, oral—The buffered
form of phenylbutazone (e.g., Alka Butazolidin) may keep these
medicines from working properly if the 2 medicines are taken too close
together
- Cyclosporine (e.g., Sandimmune) or
- Digitalis glycosides (heart
medicine) or
- Lithium (e.g., Lithane) or
- Methotrexate (e.g., Mexate) or
- Phenytoin (e.g., Dilantin)—Higher
blood levels of these medicines and an increased chance of side
effects may occur
- Penicillamine (e.g., Cuprimine)—The
chance of serious side effects may be increased, especially with
phenylbutazone (e.g., Cotylbutazone)
- Probenecid (e.g., Benemid)—Higher
blood levels of the nonsteroidal anti-inflammatory drug and an
increased chance of side effects may occur
- Triamterene (e.g., Dyrenium)—The
chance of kidney problems may be increased, especially with
indomethacin
- Zidovudine (e.g., AZT, Retrovir)—The
chance of serious side effects may be increased, especially with
indomethacin
Other medical problems-
The presence of other medical
problems may affect the use of nonsteroidal anti-inflammatory drugs.
Make sure you tell your doctor if you have any other medical problems,
especially:
- Alcohol abuse or
- Bleeding problems or
- Colitis, Crohn's disease,
diverticulitis, stomach ulcer, or other stomach or intestinal problems
or
- Diabetes mellitus (sugar diabetes)
or
- Hemorrhoids or
- Hepatitis or other liver disease or
- Kidney disease (or history of) or
- Rectal irritation or bleeding,
recent, or
- Systemic lupus erythematosus (SLE)
or
- Tobacco use (or recent history
of)—The chance of side effects may be increased
- Anemia or
- Asthma or
- Epilepsy or
- Fluid retention (swelling of feet or
lower legs) or
- Heart disease or
- High blood pressure or
- Kidney stones (or history of) or
- Low platelet count or
- Low white blood cell count or
- Mental illness or
- Parkinson's disease or
- Polymyalgia rheumatica or
- Porphyria or
- Temporal arteritis—Some nonsteroidal
anti-inflammatory drugs may make these conditions worse
- Ulcers, sores, or white spots in
mouth—Ulcers, sores, or white spots in the mouth sometimes mean that
the medicine is causing serious side effects; if these sores or spots
are already present before you start taking the medicine, it will be
harder for you and your doctor to recognize that these side effects
might be occurring
Proper Use of This Medicine
For patients taking a
capsule, tablet (including caplet), or liquid form of this medicine:
- Take tablet or capsule forms of
these medicines with a full glass (8 ounces) of water. Also, do
not lie down for about 15 to 30 minutes after taking the medicine.
This helps to prevent irritation that may lead to trouble in
swallowing.
- To lessen stomach upset, these
medicines should be taken with food or an antacid. This is especially
important when you are taking indomethacin, mefenamic acid,
phenylbutazone, or piroxicam, which should always be taken with food
or an antacid. Taking the extended-release tablet dosage form of
flurbiprofen or naproxen and taking nabumetone with food may also help
the medicine be absorbed into your body more quickly. However, your
doctor may want you to take the first 1 or 2 doses of other
nonsteroidal anti-inflammatory drugs 30 minutes before meals or 2
hours after meals. This helps the medicine start working a little
faster when you first begin to take it. However, after the first few
doses, take the medicine with food or an antacid.
- It is not necessary to take
delayed-release (enteric-coated) tablets with food or an antacid,
because the enteric coating helps protect your stomach from the
irritating effects of the medicine. Also, it is not necessary to take
ketoprofen extended-release capsules (e.g., Oruvail) with food or an
antacid, because the medicine inside the capsules is enteric coated.
- If you will be taking your medicine
together with an antacid, one that contains magnesium and aluminum
hydroxides (e.g., Maalox) may be the best kind of antacid to use,
unless your doctor has directed you to use another antacid. However,
do not mix the liquid form of ibuprofen, indomethacin, or naproxen
together with an antacid, or any other liquid, before taking it. To do
so may cause the medicine to break down. If stomach upset
(indigestion, nausea, vomiting, stomach pain, or diarrhea) continues
or if you have any questions about how you should be taking this
medicine, check with your health care professional.
- Some of these medicines must be
swallowed whole. Tablets should not be crushed, chewed, or broken, and
capsules should not be emptied out, before you take the medicine.
These include delayed-release (enteric-coated) or extended-release
tablets or capsules, diflunisal tablets (e.g., Dolobid), and
phenylbutazone tablets (e.g., Butazolidin). If you are not sure
whether you are taking a delayed-release or extended-release form of
your medicine, check with your pharmacist.
For patients using a suppository
form of this medicine:
- If the suppository is too soft to
insert, chill it in the refrigerator for 30 minutes or run cold water
over it before removing the foil wrapper.
- To insert the suppository: First
remove the foil wrapper and moisten the suppository with cold water.
Lie down on your side and use your finger to push the suppository well
up into the rectum.
- Indomethacin suppositories should be
kept inside the rectum for at least one hour so that all of the
medicine can be absorbed by your body. This helps the medicine work
better.
For patients taking nonprescription
(over-the-counter [OTC]) ibuprofen or naproxen:
- This medicine comes with a patient
information sheet. Read it carefully. If you have any questions about
this information, check with your health care professional.
For safe and effective use of this
medicine, do not take more of it, do not take it more often, and do not
take it for a longer time than ordered by your health care professional
or directed on the nonprescription (over-the-counter [OTC]) package
label
When used for severe or continuing
arthritis, a nonsteroidal anti-inflammatory drug must be taken regularly
as ordered by your doctor
For patients taking mefenamic acid:
- Always take mefenamic acid with
food or antacids .
- Do not take mefenamic acid for
more than 7 days at a time unless otherwise directed by your
doctor. To do so may increase the chance of side effects, especially
in elderly patients.
For patients taking phenylbutazone:
- Phenylbutazone is intended to treat
your current medical problem only. Do not take it for any other
aches or pains. Also, phenylbutazone should be used for the
shortest time possible because of the chance of serious side effects,
especially in patients who are 40 years of age or older.
Dosing-
The dose of these medicines will be
different for different patients. Follow your doctor's orders or the
directions on the label. The following information includes only the
average doses of these medicines. If your dose is different, do not
change it unless your doctor tells you to do so.
The number of capsules or tablets or
teaspoonfuls of suspension that you take, or the number of suppositories
that you use, depends on the strength of the medicine. Also, the
number of doses you take each day, the time allowed between doses, and
the length of time you take the medicine depend on the medical problem
for which you are taking the medicine.
People with arthritis usually need to
take more of a nonsteroidal anti-inflammatory drug during a flare-up
than they do between flare-ups of arthritis symptoms. Therefore, your
dose may need to be increased or decreased as your condition changes.
For diclofenac
- For tablet dosage form:
- For relieving pain or menstrual
cramps:
- Adults—50 milligrams (mg) three
times a day as needed. Your doctor may direct you to take 100 mg
for the first dose only.
- Children—Use and dose must be
determined by your doctor.
- For rheumatoid arthritis:
- Adults—At first, 50 mg three or
four times a day. Your doctor may increase the dose, if necessary,
up to a total of 225 mg a day. After your condition improves your
doctor may direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For osteoarthritis:
- Adults—At first, 50 mg two or
three times a day. Usually, no more than a total of 150 mg a day
should be taken. After your condition improves your doctor may
direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For spondylitis (lower back pain):
- Adults—At first, 25 mg four or
five times a day. After your condition improves your doctor may
direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For delayed-release tablet
dosage form:
- For rheumatoid arthritis:
- Adults—At first, 50 mg three or
four times a day. Your doctor may increase the dose, if necessary,
up to a total of 225 mg a day. After your condition improves your
doctor may direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For osteoarthritis:
- Adults—At first, 50 mg two or
three times a day. Usually, no more than a total of 150 mg a day
should be taken. After your condition improves your doctor may
direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For spondylitis (lower back pain):
- Adults—At first, 25 mg four or
five times a day. After your condition improves your doctor may
direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For extended-release tablet
dosage form:
- For rheumatoid arthritis,
osteoarthritis, or spondylitis:
- Adults—Usually 75 or 100 mg once
a day, in the morning or evening. Some people may need 75 mg twice
a day, in the morning and evening. Take the medicine at the same
time every day.
- Children—Use and dose must be
determined by your doctor.
- For rectal dosage form
(suppositories):
- For rheumatoid arthritis,
osteoarthritis, or spondylitis:
- Adults—One 50-mg or 100-mg
suppository, inserted into the rectum. The suppository is usually
used only at night by people who take tablets during the day.
Usually, no more than a total of 150 mg of diclofenac should be
used in a day from all dosage forms combined.
- Children—Use and dose must be
determined by your doctor.
For diflunisal
- For oral dosage form
(tablets):
- For pain:
- Adults—1000 milligrams (mg) for
the first dose, then 500 mg every eight to twelve hours as needed.
Some people may need only 500 mg for the first dose, then 250 mg
every eight to twelve hours as needed. Usually, no more than a
total of 1500 mg a day should be taken.
- Children—Dose must be determined
by your doctor.
- For rheumatoid arthritis or
osteoarthritis:
- Adults—At first, 250 or 500 mg
twice a day. Your doctor may increase the dose, if necessary, up
to a total of 1500 mg a day. After your condition improves your
doctor may direct you to take a lower dose.
- Children—Dose must be determined
by your doctor.
For etodolac
For fenoprofen
- For oral dosage forms
(capsules or tablets):
- For pain:
- Adults—200 milligrams (mg) every
four to six hours as needed.
- Children—Use and dose must be
determined by your doctor.
- For arthritis:
- Adults—At first, 300 to 600 mg
three or four times a day. Your doctor may increase the dose, if
necessary, up to a total of 3200 mg a day. After your condition
improves your doctor may direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
For floctafenine
- For oral dosage form
(tablets):
- For pain:
- Adults—200 to 400 milligrams
(mg) every six to eight hours, as needed. Usually, no more than
1200 mg a day should be taken.
- Children—Use is not recommended.
For flurbiprofen
- For oral tablet dosage form:
- For menstrual cramps:
- Adults—50 milligrams (mg) four
times a day.
- Children—Use and dose must be
determined by your doctor.
- For bursitis, tendinitis, or
athletic injuries:
- Adults—50 mg every four to six
hours as needed.
- Children—Use and dose must be
determined by your doctor.
- For rheumatoid arthritis or
osteoarthritis:
- Adults—At first, 200 to 300 mg a
day, divided into smaller amounts that are taken two to four times
a day. Usually, no more than a total of 300 mg a day should be
taken. After your condition improves your doctor may direct you to
take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For spondylitis (lower back pain):
- Adults—At first, 50 mg four
times a day. Your doctor may increase the dose, if necessary, up
to a total of 300 mg a day. After your condition improves your
doctor may direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For extended-release capsule
dosage form:
- For arthritis:
- Adults—200 mg once a day, in the
evening. Take the medicine at the same time every day.
- Children—Use and dose must be
determined by your doctor.
For ibuprofen
- For oral dosage forms (oral
suspension, tablets, chewable tablets):
- For pain or menstrual cramps:
- Adults and teenagers—200 to 400
milligrams (mg) every four to six hours as needed. If you are
taking the medicine without a prescription from your health care
professional, do not take more than a total of 1200 mg (six 200-mg
tablets) a day.
- Children up to 12 years of
age—Use and dose must be determined by your doctor.
- For fever:
- Adults and teenagers—200 to 400
mg every four to six hours as needed. If you are taking the
medicine without a prescription from your health care
professional, do not take more than a total of 1200 mg (six 200-mg
tablets) a day.
- Children 6 months to 12 years of
age—The medicine should be used only with a prescription from your
doctor. The dose is based on body weight and on the body
temperature. For fevers lower than 102.5 °F (39.2 °C) the dose is
5 mg per kilogram (kg) (about 2.2 mg per pound) of body weight.
For higher fevers the dose is 10 mg per kg (about 4.5 mg per
pound) of body weight.
- Infants younger than 6 months of
age—Use and dose must be determined by your doctor.
- For arthritis:
- Adults and teenagers—At first, a
total of 1200 to 3200 mg a day, divided into smaller amounts that
are taken three or four times a day. After your condition improves
your doctor may direct you to take a lower dose.
- Children 6 months to 12 years of
age—The dose is based on body weight. At first, a total of 30 to
40 mg per kg (about 13.6 to 18 mg per pound) of body weight a day,
divided into smaller amounts that are taken three or four times a
day. Your doctor may increase the dose, if necessary, up to a
total of 50 mg per kg (about 21 mg per pound) of body weight a
day. After your condition improves your doctor may direct you to
take a lower dose.
- Infants younger than 6 months of
age—Use and dose must be determined by your doctor.
For indomethacin
- For capsule or oral suspension
dosage forms:
- For arthritis:
- Adults—At first, 25 or 50
milligrams (mg) two to four times a day. Your doctor may increase
the dose, if necessary, up to a total of 200 mg a day. After your
condition improves your doctor may direct you to take a lower
dose.
- Children—The dose is based on
body weight. At first, 1.5 to 2.5 mg per kilogram (kg) (about 0.7
to 1.1 mg per pound) of body weight a day, divided into smaller
amounts that are taken three or four times a day. Your doctor may
increase the dose, if necessary, up to a total of 4 mg per kg
(about 1.8 mg per pound) of body weight or 200 mg a day, whichever
is less. After your condition improves your doctor may direct you
to take a lower dose.
- For gout:
- Adults—100 mg for the first
dose, then 50 mg three times a day. After the pain is relieved,
your doctor may direct you to take a lower dose for a while before
stopping treatment completely.
- Children—Use and dose must be
determined by your doctor.
- For bursitis or tendinitis:
- Adults—25 mg three or four times
a day or 50 mg three times a day.
- Children—Use and dose must be
determined by your doctor.
- For extended-release capsule
dosage form:
- For arthritis:
- Adults—75 mg once a day, in the
morning or evening. Some people may need to take 75 mg twice a
day, in the morning and evening. Take the medicine at the same
time each day.
- Children—Dose must be determined
by your doctor.
- For rectal suppository dosage
form:
- For arthritis, bursitis,
tendinitis, or gout:
- Adults—One 50-mg suppository,
inserted into the rectum up to four times a day.
- Children—One 50-mg suppository,
inserted into the rectum up to four times a day. The suppository
dosage form is too strong for small children. However, the
suppositories may be used for large or heavy children if they need
doses as large as 50 mg.
For ketoprofen
- For capsule, tablet, or
delayed-release tablet dosage forms:
- For pain or menstrual cramps:
- Adults—25 to 50 milligrams (mg)
every six to eight hours as needed. Some people may need to take
as much as 75 mg every six to eight hours. Doses larger than 75 mg
are not likely to give better relief.
- Over-the-counter medication—12.5
mg every 4 to 6 hours.
- Children—Use and dose must be
determined by your doctor.
- For arthritis:
- Adults—At first, 50 mg four
times a day or 75 mg three times a day. Your doctor may increase
the dose, if necessary, up to a total of 300 mg a day. After your
condition improves your doctor may direct you to take a lower
dose.
- Children—Use and dose must be
determined by your doctor.
- For extended-release capsule or
extended-release tablet dosage forms:
- For arthritis:
- Adults—150 or 200 mg once a day,
in the morning or evening. Take the medicine at the same time
every day.
- Children—Use and dose must be
determined by your doctor.
- For rectal suppository dosage
form:
- For arthritis:
- Adults—50 or 100 mg twice a day,
inserted into the rectum, in the morning and evening. Sometimes,
the suppository is used only at night by people who take an oral
dosage form (capsules or delayed-release tablets) during the day.
Usually, no more than a total of 300 mg of ketoprofen should be
used in a day from all dosage forms combined.
- Children—Use and dose must be
determined by your doctor.
For meclofenamate
- For oral dosage form
(capsules):
- For arthritis:
- Adults and teenagers 14 years of
age and older—At first, 50 milligrams (mg) four times a day. Your
doctor may increase the dose, if necessary, up to a total of 400
mg a day. After your condition improves your doctor may direct you
to take a lower dose.
- Children up to 14 years of
age—Use and dose must be determined by your doctor.
- For pain:
- Adults and teenagers 14 years of
age and older—50 mg every four to six hours. Some people may need
as much as 100 mg every four to six hours.
- Children up to 14 years of
age—Use and dose must be determined by your doctor.
- For menstrual cramps and heavy
menstrual bleeding:
- Adults and teenagers 14 years of
age and older—100 mg three times a day for up to six days.
- Children up to 14 years of
age—Use and dose must be determined by your doctor.
For mefenamic acid
- For oral dosage form
(capsules):
- For pain and for menstrual cramps:
- Adults and teenagers 14 years of
age and older—500 milligrams (mg) for the first dose, then 250 mg
every six hours as needed for up to seven days.
- Children up to 14 years of
age—Use and dose must be determined by your doctor.
For meloxicam
- For oraldosage form
(tablets):
- For osteoarthritis:
- Adults—7.5 milligrams (mg) daily
in a single dose.
For nabumetone
- For oral dosage form
(tablets):
- For arthritis:
- Adults—At first, 1000 milligrams
(mg) once a day, in the morning or evening, or 500 mg twice a day,
in the morning and evening. Your doctor may increase the dose, if
necessary, up to a total of 2000 mg a day. After your condition
improves your doctor may direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
For naproxen
- For naproxen (e.g., Naprosyn)
tablet, oral suspension, and delayed-release tablet dosage forms:
- For arthritis:
- Adults—At first, 250, 375, or
500 milligrams (mg) two times a day, in the morning and evening.
Your doctor may increase the dose, if necessary, up to a total of
1500 mg a day. After your condition improves your doctor may
direct you to take a lower dose.
- Children—The dose is based on
body weight. At first, 5 mg per kilogram (kg) (about 2.25 mg per
pound) of body weight twice a day. After your condition improves
your doctor may direct you to take a lower dose.
- For bursitis, tendinitis,
menstrual cramps, and other kinds of pain:
- Adults—500 mg for the first
dose, then 250 mg every six to eight hours as needed.
- Children—Use and dose must be
determined by your doctor.
- For gout:
- Adults—750 mg for the first
dose, then 250 mg every eight hours until the attack is relieved.
- Children—Use and dose must be
determined by your doctor.
- For naproxen extended-release
tablet (e.g., Naprelan) dosage form:
- For arthritis and pain:
- Adults—750 to 1000 mg once a
day, in the morning or evening.
- Children—The extended-release
tablets are too strong for use in children.
- For naproxen (e.g., Naprosyn)
rectal suppository dosage form:
- For arthritis:
- Adults—One 500-mg suppository,
inserted into the rectum at bedtime. The suppository is usually
used only at night by people who take an oral dosage form
(tablets, oral suspension, or delayed-release tablets) during the
day. Usually, no more than a total of 1500 mg of naproxen should
be used in a day from all dosage forms combined.
- Children—The suppositories are
too strong for use in children.
- For naproxen sodium (e.g., Aleve,
Anaprox) tablet dosage form:
- For arthritis:
- Adults—At first, 275 or 550 mg
two times a day, in the morning and evening, or 275 mg in the
morning and 550 mg in the evening. Your doctor may increase the
dose, if necessary, up to a total of 1650 mg a day. After your
condition improves your doctor may direct you to take a lower
dose.
- Children—Naproxen sodium tablets
are too strong for most children. Naproxen (e.g., Naprosyn)
tablets or oral suspension are usually used for children.
- For bursitis and tendinitis:
- Adults—550 mg for the first
dose, then 275 mg every six to eight hours as needed.
- Children—Use and dose must be
determined by your doctor. Naproxen sodium tablets are too strong
for most children.
- For gout:
- Adults—825 mg for the first
dose, then 275 mg every eight hours until the attack is relieved.
- Children—Use and dose must be
determined by your doctor. Naproxen sodium tablets are too strong
for most children.
- For pain, fever, and menstrual
cramps:
- Adults and children 12 years of
age or older—For nonprescription (over-the-counter [OTC]) use: 220
mg (one tablet) every eight to twelve hours as needed. Some people
may get better relief if they take 440 mg (two tablets) for the
first dose, then 220 mg twelve hours later on the first day only.
If you are taking this medicine without a prescription from your
health care professional, do not take more than three 220-mg
tablets a day. If you are older than 65 years of age, do not take
more than two 220-mg tablets a day. Your health care professional
may direct you to take larger doses.
- Children up to 12 years of
age—Use and dose must be determined by your doctor.
For oxaprozin
- For oral dosage form
(tablets):
- For arthritis:
- Adults—At first, 600 milligrams
(mg) once or twice a day, or 1200 mg once a day. Some people may
need a larger amount for the first dose only. Your doctor may
increase the dose, if necessary, up to 1800 mg a day. This large
dose should always be divided into smaller amounts that are taken
two or three times a day. After your condition improves your
doctor may direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
For phenylbutazone
- For oral dosage forms
(capsules, tablets, and buffered tablets):
- For severe arthritis:
- Adults and teenagers 15 years of
age and older—At first, 100 milligrams (mg) three or four times a
day. Some people may need a higher dose of 200 mg three times a
day. After your condition improves your doctor may direct you to
take a lower dose for a while before stopping treatment
completely. This medicine should not be taken for longer than a
few weeks.
- Children up to 15 years of
age—Use is not recommended.
- For gout:
- Adults—400 mg for the first
dose, then 100 mg every four hours for one week or less.
- Children up to 15 years of
age—Use is not recommended.
For piroxicam
- For oral dosage form
(capsules):
- For arthritis:
- Adults—20 milligrams (mg) once a
day or 10 mg twice a day.
- Children—Dose must be determined
by your doctor.
- For menstrual cramps:
- Adults—40 mg once a day for one
day only, then 20 mg once a day if needed.
- Children—Dose must be determined
by your doctor.
- For rectal dosage form
(suppositories):
- For arthritis:
- Adults—20 mg once a day or 10 mg
twice a day.
- Children—Dose must be determined
by your doctor.
For sulindac
- For oral dosage form
(tablets):
- For arthritis:
- Adults—At first, 150 or 200
milligrams (mg) twice a day. After your condition improves, your
doctor may direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For gout, bursitis, or tendinitis:
- Adults—At first, 200 mg twice a
day. After the pain is relieved, your doctor may direct you to
take a lower dose for a while before treatment is stopped
completely.
- Children—Use and dose must be
determined by your doctor.
For tenoxicam
- For oral dosage form
(tablets):
- For arthritis:
- Adults and teenagers 16 years of
age and older—At first, 20 milligrams (mg) once a day, at the same
time each day. For some people, a smaller dose of 10 mg (one-half
tablet) a day may be enough.
- Children and teenagers up to 16
years of age—Dose must be determined by your doctor.
For tiaprofenic acid
- For oral tablet dosage form:
- For arthritis:
- Adults—At first, 200 milligrams
(mg) three times a day or 300 mg twice a day. After your condition
improves, your doctor may direct you to take a lower dose.
- Children—Use and dose must be
determined by your doctor.
- For extended-release capsule
dosage form:
- For arthritis:
- Adults—600 mg (two capsules)
once a day, at the same time each day.
- Children—Use and dose must be
determined by your doctor.
For tolmetin
- For oral dosage forms
(capsules or tablets):
- For arthritis:
- Adults—At first, 400 milligrams
(mg) three times a day. Your doctor may increase the dose, if
necessary, up to a total of 1800 mg a day. After your condition
improves, your doctor may direct you to take a lower dose.
- Children 2 years of age and
older—The dose is based on body weight. At first, 20 mg per
kilogram (kg) (about 9 mg per pound) of body weight a day, divided
into smaller amounts that are taken three or four times a day.
Your doctor may increase the dose, if necessary, up to 30 mg per
kg (about 13.5 mg per pound) of body weight a day. After your
condition improves, your doctor may direct you to take a lower
dose.
- Children up to 2 years of
age—Dose must be determined by your doctor.
Missed dose-
If your health care professional has ordered you to take
this medicine according to a regular schedule, and you miss a dose, take
it as soon as you remember. However, if it is almost time for your next
dose, skip the missed dose and go back to your regular dosing schedule.
(For long-acting medicines or extended-release dosage forms that are
only taken once or twice a day, take the missed dose only if you
remember within an hour or two after the dose should have been taken. If
you do not remember until later, skip the missed dose and go back to
your regular dosing schedule.) Do not double doses.
Storage-
To store this medicine:
- Keep out of the reach of children.
- Store away from heat and direct
light.
- Do not store tablets or capsules in
the bathroom, near the kitchen sink, or in other damp places. Heat or
moisture may cause the medicine to break down.
- Keep liquid and suppository forms of
this medicine from freezing.
- Do not keep outdated medicine or
medicine no longer needed. Be sure that any discarded medicine is out
of the reach of children.
Precautions While Using This Medicine
If you will be taking this
medicine for a long time, as for arthritis (rheumatism), your doctor
should check your progress at regular visits
Stomach problems may be more likely to
occur if you drink alcoholic beverages while being treated with this
medicine. Also, alcohol may add to the depressant side effects of
phenylbutazone.
If you consume 3 or more alcoholic
beverages per day, check with your doctor
Taking two or more of the nonsteroidal
anti-inflammatory drugs together on a regular basis may increase the
chance of unwanted effects. Also, taking acetaminophen, aspirin or other
salicylates, or ketorolac (e.g., Toradol) regularly while you are taking
a nonsteroidal anti-inflammatory drug may increase the chance of
unwanted effects. The risk will depend on how much of each medicine you
take every day, and on how long you take the medicines together. If your
health care professional directs you to take these medicines together on
a regular basis, follow his or her directions carefully. However, do
not take acetaminophen or aspirin or other salicylates together with
this medicine for more than a few days, and do not take any ketorolac
(e.g., Toradol) while you are taking this medicine, unless your doctor
has directed you to do so and is following your progress.
Before having any kind of surgery
(including dental surgery), tell the medical doctor or dentist in charge
that you are taking this medicine. If possible, this should be done when
your surgery is first being planned. Some of the nonsteroidal
anti-inflammatory drugs can increase the chance of bleeding during and
after surgery. It may be necessary for you to stop treatment for a
while, or to change to a different nonsteroidal anti-inflammatory drug
that is less likely to cause bleeding.
This medicine may cause some people to
become confused, drowsy, dizzy, lightheaded, or less alert than they are
normally. It may also cause blurred vision or other vision problems in
some people. Make sure you know how you react to this medicine before
you drive, use machines, or do anything else that could be dangerous if
you are confused, dizzy, or drowsy, or if you are not alert and able to
see well. If these reactions are especially bothersome, check with
your doctor.
For patients taking the buffered
form of phenylbutazone (e.g., Alka-Butazolidin):
- This medicine contains antacids that
can keep other medicines from working properly if the 2 medicines are
taken too close together. Always take this medicine:
- At least 6 hours before or 2
hours after taking ciprofloxacin (e.g., Cipro) or lomefloxacin
(e.g., Maxaquin).
- At least 8 hours before or 2
hours after taking enoxacin (e.g., Penetrex).
- At least 2 hours after taking
itraconazole (e.g., Sporanox).
- At least 3 hours before or
after taking ketoconazole (e.g., Nizoral).
- At least 2 hours before or
after taking norfloxacin (e.g., Noroxin) or ofloxacin (e.g., Floxin).
- At least 1 to 3 hours before or
after taking a tetracycline antibiotic by mouth.
- At least 1 or 2 hours before or
after taking any other medicine by mouth.
For patients taking mefenamic acid:
- If diarrhea occurs while you are
using this medicine, stop taking it and check with your doctor
immediately. Do not take it again without first checking with your
doctor, because severe diarrhea may occur each time you take it.
Some people who take nonsteroidal
anti-inflammatory drugs may become more sensitive to sunlight than they
are normally. Exposure to sunlight, even for brief periods of time, may
cause severe sunburn; blisters on the skin; skin rash, redness, itching,
or discoloration; or vision changes. When you begin taking this
medicine:
- Stay out of direct sunlight,
especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
- Wear protective clothing, including
a hat and sunglasses.
- Apply a sun block product that has a
skin protection factor (SPF) of at least 15. Some patients may require
a product with a higher SPF number, especially if they have a fair
complexion. If you have any questions about this, check with your
health care professional.
- Do not use a sunlamp or tanning bed
or booth.
If you have a severe reaction from the
sun, check with your doctor.
Serious side effects, including ulcers
or bleeding, can occur during treatment with this medicine. Sometimes
serious side effects can occur without any warning. However, possible
warning signs often occur, including severe abdominal or stomach cramps,
pain, or burning; black, tarry stools; severe, continuing nausea,
heartburn, or indigestion; and/or vomiting of blood or material that
looks like coffee grounds. Stop taking this medicine and check with
your doctor immediately if you notice any of these warning signs.
Check with your doctor immediately
if chills, fever, muscle aches or pains, or other influenza-like
symptoms occur, especially if they occur shortly before, or together
with, a skin rash
Nonsteroidal anti-inflammatory drugs
may cause a serious type of allergic reaction called anaphylaxis.
Although this is rare, it may occur more often in patients who are
allergic to aspirin or to any of the nonsteroidal anti-inflammatory
drugs. Anaphylaxis requires immediate medical attention . The
most serious signs of this reaction are very fast or irregular
breathing, gasping for breath, wheezing, or fainting. Other signs may
include changes in color of the skin of the face; very fast but
irregular heartbeat or pulse; hive-like swellings on the skin; and
puffiness or swellings of the eyelids or around the eyes. If these
effects occur, get emergency help at once. Ask someone to drive you to
the nearest hospital emergency room. If this is not possible, do not try
to drive yourself. Call an ambulance, lie down, cover yourself to keep
warm, and prop your feet higher than your head. Stay in that position
until help arrives.
For patients taking ibuprofen or
naproxen without a prescription:
- Check with your medical doctor or
dentist:
- if your symptoms do not improve or
if they get worse.
- if you are using this medicine to
bring down a fever and the fever lasts more than 3 days or returns.
- if the painful area is red or
swollen.
This medicine may cause some people to become drowsy, dizzy, or
lightheaded, or to feel a false sense of well-being. Make sure you know
how you react to this medicine before you drive, use machines, or do
anything else that could be dangerous if you are dizzy or are not alert
and clearheaded.
Dizziness, lightheadedness, or fainting may occur, especially when you
get up suddenly from a lying or sitting position. Getting up slowly may
help lessen this problem.
Nausea or vomiting may occur, especially after the first couple of
doses. This effect may go away if you lie down for a while. However, if
nausea or vomiting continues, check with your medical doctor or dentist.
Lying down for a while may also help relieve some other side effects,
such as dizziness or lightheadedness, that may occur.
Before having any kind of surgery (including dental surgery) or
emergency treatment, tell the medical doctor or dentist in charge that
you are taking this medicine.
Narcotic analgesics may cause dryness of the mouth. For temporary
relief, use sugarless candy or gum, melt bits of ice in your mouth, or
use a saliva substitute. However, if dry mouth continues for more than 2
weeks, check with your dentist. Continuing dryness of the mouth may
increase the chance of dental disease, including tooth decay, gum
disease, and fungus infections.
If you have been taking this medicine regularly for several weeks or
more, do not suddenly stop taking it without first checking with your
doctor. Your doctor may want you to reduce gradually the amount you are
taking before stopping completely, to lessen the chance of withdrawal
side effects. This will depend on which of these medicines you have been
taking, and the amount you have been taking every day.
If you think you or someone else may have taken an overdose of this
medicine, get emergency help at once
Side Effects of This Medicine
If you will be taking this
medicine for a long time, as for arthritis (rheumatism), your doctor
should check your progress at regular visits
Stomach problems may be more likely to
occur if you drink alcoholic beverages while being treated with this
medicine. Also, alcohol may add to the depressant side effects of
phenylbutazone.
If you consume 3 or more alcoholic
beverages per day, check with your doctor
Taking two or more of the nonsteroidal
anti-inflammatory drugs together on a regular basis may increase the
chance of unwanted effects. Also, taking acetaminophen, aspirin or other
salicylates, or ketorolac (e.g., Toradol) regularly while you are taking
a nonsteroidal anti-inflammatory drug may increase the chance of
unwanted effects. The risk will depend on how much of each medicine you
take every day, and on how long you take the medicines together. If your
health care professional directs you to take these medicines together on
a regular basis, follow his or her directions carefully. However, do
not take acetaminophen or aspirin or other salicylates together with
this medicine for more than a few days, and do not take any ketorolac
(e.g., Toradol) while you are taking this medicine, unless your doctor
has directed you to do so and is following your progress.
Before having any kind of surgery
(including dental surgery), tell the medical doctor or dentist in charge
that you are taking this medicine. If possible, this should be done when
your surgery is first being planned. Some of the nonsteroidal
anti-inflammatory drugs can increase the chance of bleeding during and
after surgery. It may be necessary for you to stop treatment for a
while, or to change to a different nonsteroidal anti-inflammatory drug
that is less likely to cause bleeding.
This medicine may cause some people to
become confused, drowsy, dizzy, lightheaded, or less alert than they are
normally. It may also cause blurred vision or other vision problems in
some people. Make sure you know how you react to this medicine before
you drive, use machines, or do anything else that could be dangerous if
you are confused, dizzy, or drowsy, or if you are not alert and able to
see well. If these reactions are especially bothersome, check with
your doctor.
For patients taking the buffered
form of phenylbutazone (e.g., Alka-Butazolidin):
- This medicine contains antacids that
can keep other medicines from working properly if the 2 medicines are
taken too close together. Always take this medicine:
- At least 6 hours before or 2
hours after taking ciprofloxacin (e.g., Cipro) or lomefloxacin
(e.g., Maxaquin).
- At least 8 hours before or 2
hours after taking enoxacin (e.g., Penetrex).
- At least 2 hours after taking
itraconazole (e.g., Sporanox).
- At least 3 hours before or
after taking ketoconazole (e.g., Nizoral).
- At least 2 hours before or
after taking norfloxacin (e.g., Noroxin) or ofloxacin (e.g., Floxin).
- At least 1 to 3 hours before or
after taking a tetracycline antibiotic by mouth.
- At least 1 or 2 hours before or
after taking any other medicine by mouth.
For patients taking mefenamic acid:
- If diarrhea occurs while you are
using this medicine, stop taking it and check with your doctor
immediately. Do not take it again without first checking with your
doctor, because severe diarrhea may occur each time you take it.
Some people who take nonsteroidal
anti-inflammatory drugs may become more sensitive to sunlight than they
are normally. Exposure to sunlight, even for brief periods of time, may
cause severe sunburn; blisters on the skin; skin rash, redness, itching,
or discoloration; or vision changes. When you begin taking this
medicine:
- Stay out of direct sunlight,
especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
- Wear protective clothing, including
a hat and sunglasses.
- Apply a sun block product that has a
skin protection factor (SPF) of at least 15. Some patients may require
a product with a higher SPF number, especially if they have a fair
complexion. If you have any questions about this, check with your
health care professional.
- Do not use a sunlamp or tanning bed
or booth.
If you have a severe reaction from the
sun, check with your doctor.
Serious side effects, including ulcers
or bleeding, can occur during treatment with this medicine. Sometimes
serious side effects can occur without any warning. However, possible
warning signs often occur, including severe abdominal or stomach cramps,
pain, or burning; black, tarry stools; severe, continuing nausea,
heartburn, or indigestion; and/or vomiting of blood or material that
looks like coffee grounds. Stop taking this medicine and check with
your doctor immediately if you notice any of these warning signs.
Check with your doctor immediately
if chills, fever, muscle aches or pains, or other influenza-like
symptoms occur, especially if they occur shortly before, or together
with, a skin rash
Nonsteroidal anti-inflammatory drugs
may cause a serious type of allergic reaction called anaphylaxis.
Although this is rare, it may occur more often in patients who are
allergic to aspirin or to any of the nonsteroidal anti-inflammatory
drugs. Anaphylaxis requires immediate medical attention . The
most serious signs of this reaction are very fast or irregular
breathing, gasping for breath, wheezing, or fainting. Other signs may
include changes in color of the skin of the face; very fast but
irregular heartbeat or pulse; hive-like swellings on the skin; and
puffiness or swellings of the eyelids or around the eyes. If these
effects occur, get emergency help at once. Ask someone to drive you to
the nearest hospital emergency room. If this is not possible, do not try
to drive yourself. Call an ambulance, lie down, cover yourself to keep
warm, and prop your feet higher than your head. Stay in that position
until help arrives.
For patients taking ibuprofen or
naproxen without a prescription:
- Check with your medical doctor or
dentist:
- if your symptoms do not improve or
if they get worse.
- if you are using this medicine to
bring down a fever and the fever lasts more than 3 days or returns.
- if the painful area is red or
swollen.
Some commonly used brand names are:
In the U.S.-
- Actron
- Advil
- Advil Caplets
- Advil, Children's
- Aleve
- Anaprox
- Anaprox DS
- Ansaid
- Bayer Select Ibuprofen Pain Relief Formula Caplets
- Cataflam
- Clinoril
- Cotylbutazone
- Cramp End
- Daypro
- Dolgesic
- Dolobid
- EC-Naprosyn
- Excedrin IB
- Excedrin IB Caplets
- Feldene
- Genpril
- Genpril Caplets
- Haltran
- Ibifon 600 Caplets
- Ibren
- Ibu
- Ibu-200
- Ibu-4
- Ibu-6
- Ibu-8
- Ibuprin
- Ibuprohm
- Ibuprohm Caplets
- Ibu-Tab
- Indocin
|
- Indocin SR
- Lodine
- Lodine XL
- Meclomen
- Medipren
- Medipren Caplets
- Midol IB
- Mobic
- Motrin
- Motrin Chewables
- Motrin, Children's
- Motrin, Children's Oral Drops
- Motrin-IB
- Motrin-IB Caplets
- Motrin, Junior Strength Caplets
- Nalfon
- Nalfon 200
- Naprelan
- Naprosyn
- Nuprin
- Nuprin Caplets
- Orudis
- Orudis KT
- Oruvail
- Pamprin-IB
- Ponstel
- Q-Profen
- Relafen
- Rufen
- Tolectin 200
- Tolectin 600
- Tolectin DS
- Trendar
- Voltaren
|
In Canada-
- Actiprofen Caplets
- Advil
- Advil Caplets
- Albert Tiafen
- Alka Butazolidin
- Anaprox
- Anaprox DS
- Ansaid
- Apo-Diclo
- Apo-Diflunisal
- Apo-Flurbiprofen
- Apo-Ibuprofen
- Apo-Indomethacin
- Apo-Keto
- Apo-Keto-E
- Apo-Napro-Na
- Apo-Napro-Na DS
- Apo-Naproxen
- Apo-Phenylbutazone
- Apo-Piroxicam
- Apo-Sulin
- Apo-Tenoxicam
- Butazolidin
- Clinoril
- Daypro
- Dolobid
- Feldene
- Froben
- Froben SR
- Idarac
- Indocid
- Indocid SR
- Medipren Caplets
- Mobiflex
- Motrin
- Motrin-IB
- Nalfon
- Naprosyn
- Naprosyn-E
- Naprosyn-SR
|
- Naxen
- Novo-Difenac
- Novo-Difenac SR
- Novo-Diflunisal
- Novo-Flurprofen
- Novo-Keto-EC
- Novo-Methacin
- Novo-Naprox
- Novo-Naprox Sodium
- Novo-Naprox Sodium DS
- Novo-Pirocam
- Novo-Profen
- Novo-Sundac
- Novo-Tenoxicam
- Novo-Tolmetin
- Nu-Diclo
- Nu-Flurbiprofen
- Nu-Ibuprofen
- Nu-Indo
- Nu-Naprox
- Nu-Pirox
- Orudis
- Orudis-E
- Orudis-SR
- Oruvail
- PMS-Piroxicam
- Ponstan
- Relafen
- Rhodis
- Rhodis-EC
- Surgam
- Surgam SR
- Synflex
- Synflex DS
- Tolectin 200
- Tolectin 400
- Tolectin 600
- Voltaren
- Voltaren Rapide
- Voltaren SR
|
|
